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办公地址:无锡市锡山区东安路88号B栋5楼

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吴锦慧/ Wu Jinhui

副所长

电子邮件:wuj@nju.edu.cn

联系电话:025-83592629

通讯地址:

人物简历

研究领域

承担项目

代表论著

教育及工作经历

2006.09-2010.08 南京大学生命科学学院博士(药学)

2010.11-至今 南京大学生科院/医学院讲师、副教授、教授 博士生导师

2022-至今 无锡市南京大学锡山应用生物技术研究所 副所长,研究员


获奖情况

2020年 教育部自然科学一等奖(第2完成人);

2019年 中国专利优秀奖;

2018年 江苏省专利金奖;

2017年 教育部技术发明一等奖(第2完成人);

2018年 江苏省医药科技杰出青年奖;

2014年 高校“青蓝工程”优秀青年骨干教师;

江苏省六大人才高峰计划高层次人才;

南京大学青年五四奖章;



研究领域:核酸药物与靶向制剂

   针对难溶性、高毒性等药物的成药性,开发可工业化的药物制剂制备技术与工艺路线,确立关键工艺参数和验证方案,并建立符合现代药品监管法规的药物制剂质量评价方法和标准。 

1. 国家自然科学面上基金(32171372)

2. 国家自然科学面上基金(31872755)

3. 国家自然科学青年基金(81202474)

4. 江苏省杰出青年基金(BK20190007)

5. 江苏省自然科学基金(BK2011572)

6. 国家重点研发计划前沿生物技术(2022)


1. Yang Liu, Yuchen Wang, Chao Wang, Tiejun Dong, Haiheng Xu, Yunfei Guo, Xiaozhi Zhao, Yiqiao Hu, Jinhui Wu*, Hijacking Self-Assembly to Establish Intracellular Functional Nanoparticles. Advanced Science. 2022 Sep 8;e2203027

2. Zhuo Feng, Yuchen Wang, Haiheng Xu, Yunfei Guo, Wen Xia, Chenxuan Zhao, Xiaozhi Zhao, Jinhui Wu*, Recent advances in bacterial therapeutics based on sense and response. Acta Pharmaceutica Sinica B, 2022

3. Wenjing Zai, Lin Kang, Tiejun Dong, Haoran Wang, Lining Yin, Shaoju Gan, Wenjia Lai, Yibing Ding, Yiqiao Hu, Jinhui Wu*. E. coli Membrane Vesicles as Catalase Carrier for Long Term Tumor Hypoxia Relief to Enhance Radiotherapy. ACS Nano, 2021, 15, 9, 15381–15394.

4. Wenguang Wang, Haiheng Xu, Qingsong Ye, Feng Tao, Ian Wheeldon, Ahu Yuan, Yiqiao Hu, Jinhui Wu*, Systemic immune responses to irradiated tumours via the transport of antigens to the tumour periphery by injected flagellate bacteria. Nature Biomedical Engineering. 2021

5. Chao Wang, Zhaoyi Sun, Chenxuan Zhao, Zhewei Zhang, Haoran Wang, Yang Liu, Yunfei Guo, Bingtao Zhang, Lihong Gu, Yue Yu, Yiqiao Hu, Jinhui Wu*. Maintaining manganese in tumor to activate cGAS-STING pathway evokes a robust abscopal anti-tumor effect. Journal of Controlled Release, 2021,331,480

6. Haoran Wang, Yunfei Guo, Shaoju Gan, Honghui Liu, Qian Chen, Ahu Yuan, Yiqiao Hu, Jinhui Wu*. Photosynthetic Microorganisms‐Based Biophotothermal Therapy with Enhanced Immune Response. Small, 17, 2007734

7. Haoran Wang, Yunfei Guo,ChaoWang,Xing Jiang,Honghui Liu,Ahu Yuan,Jing Yan,Yiqiao Hu,Jinhui Wu*. Light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia. Biomaterials, 269, 120621

8. Huanhuan Chen, Yuhao Cheng, Jingrun Tian, Peizheng Yang, Xuerao Zhang, Yunhao Chen, Yiqiao Hu*, Jinhui Wu*. Dissolved oxygen from microalgae-gel patch promotes chronic wound healing in diabetes. Science Advances, 2020, 6(20), eaba4311

9. Zaigang Zhou, Baoli Zhang, Wenjing Zai, Lin Kang, Ahu Yuan, Yiqiao Hu*, Jinhui Wu*, Perfluorocarbon nanoparticle-mediated platelet inhibition promotes intratumoral infiltration of T cells and boosts immunotherapy. PNAS, 2019 May 29. pii: 201901987.

10. Wenguang Wang, Yuhao Cheng, Peng Yu, Haoran Wang, Yue Zhang, Haiheng Xu, Qingsong Ye, Ahu Yuan, Yiqiao Hu, Jinhui Wu*, Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy. Nature communications. 2019, 10:1580.

11. Yuhao Cheng, Hao Cheng, Chenxiao Jiang, Xuefeng Qiu, Kaikai Wang, Wei Huan, Ahu Yuan, Jinhui Wu*, Yiqiao Hu*; Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy; Nature communications; 2015 Nov 3, 6:8785;

*: 通讯作者或者共同通讯作者