教育及工作经历

1996 南京大学高分子专业博士学位,

1993-1995 日本京都大学博士生,

1997-1999 新加坡国立大学访问学者兼微电子研究所研究员。

2017.10 南京大学医学院院长。

2018.12 南京大学党委常委、副校长

 获奖情况

1. 2024. 国家自然科学二等奖

2. 2012. 长江学者特聘教授

3. 2011. 教育部科学技术一等奖

4. 2010. 国家杰出青年科学基金

5. 2004. 国家自然科学二等奖

       材料表面纳米结构修饰和分子设计在生物材料和微电子材料上的应用；纳米非病毒载体对基因的转移和细胞内导入；基因和蛋白质多肽药物的靶向和控制释放。

1. Ji S, Wang F, Wu Y, Hu H, Xing Z, Zhu J, Xu S, Han T, Liu G, Wu Z, Fei C, Kong L, Chen J, Ding Z*, Huang Z*, Zhang J*. Large-scale transcript variants dictate neoepitopes for cancer immunotherapy. Sci Adv. 2025;11(5):eado5600.

2. Zhao M, Cheng X, Shao P, Dong Y, Wu Y, Xiao L, Cui Z, Sun X, Gao C, Chen J*, Huang Z*, Zhang J*. Bacterial protoplast-derived nanovesicles carrying CRISPR-Cas9 tools re-educate tumor-associated macrophages for enhanced cancer immunotherapy. Nat Commun. 2024;15(1):950.

3. Cheng X, Shao P, Wang X, Jiang J, Chen J, Zhu J, Zhu W, Li Y*, Zhang J*, Chen J*, Huang Z*. Myeloid-Derived Suppressor Cell Accumulation Drives Intestinal Fibrosis through mCCL6/hCCL15 Chemokine-Mediated Fibroblast Activation. Adv Sci (Weinh). 2024:e2411711.

4. Wang L, Sun Y, Yang L, Wang S, Liu C, Wang Y, Niu Y, Huang Z, Zhang J*, Wang C*, Dong L*. Engineering an energy-dissipating hybrid tissue in vivo for obesity treatment. Cell Rep. 2024;43(7):114425.

5. Kang Z, Wang C, Shao F, Deng H, Sun Y, Ren Z, Zhang W, Ding Z, Zhang J*, Zang Y*. The increase of long noncoding RNA Fendrr in hepatocytes contributes to liver fibrosis by promoting IL-6 production. J Biol Chem. 2024;300(6):107376.

6. Xing Z, Xue J, Ma X, Han C, Wang Z, Luo S, Wang C, Dong L, Zhang J. Intracellular mRNA phase separation induced by cationic polymers for tumor immunotherapy. J Nanobiotechnology. 2022;20(1):442.

7. Liu C, Wang L, Xu M, Sun Y, Xing Z, Zhang J*, Wang C*, Dong L*. Reprogramming the spleen into a functioning 'liver' in vivo. Gut. 2022;71(11):2325-2336.

8. Wang Y, Pang J, Wang Q, Yan L, Wang L, Xing Z, Wang C*, Zhang J*, Dong L*. Delivering Antisense Oligonucleotides across the Blood-Brain Barrier by Tumor Cell-Derived Small Apoptotic Bodies. Adv Sci (Weinh). 2021;8(13):2004929.

9. Wang L, Wang C, Wang Z, Gan J, Liu C, Xia S, Niu Y, Chen D, Zhang J*, Dong L*. Transforming the spleen into a liver-like organ in vivo.  Sci Adv. 2020;6(24):eaaz9974.

10. He W, Xu J, Mu R, Li Q, Lv DL, Huang Z, Zhang J*, Wang C*, Dong L*. High-salt diet inhibits tumour growth in mice via regulating myeloid-derived suppressor cell differentiation. Nat Commun. 2020;11(1):1732.